Day 5 of 99 Days to FASDay: No Known Safe Amount of Alcohol During Pregnancy


An article published in The Guardian on May 18, 2017 caused some controversy and discussion.

Warning pregnant women over dangers of alcohol goes too far, experts say

In the article various organizations and “experts” (in particular The British Pregnancy Advisory Service) feel the message of no alcohol during pregnancy scares women and is not based on reliable evidence.

Women are being unfairly alarmed by official guidelines that warn them to avoid alcohol completely during pregnancy, experts claim. Some mothers-to-be may even be having an abortion because they are worried they have damaged their unborn child by drinking too much, it is claimed.

“We need to think hard about how risk is communicated to women on issues relating to pregnancy. There can be real consequences to overstating evidence or implying certainty when there isn’t any,” said Clare Murphy, director of external affairs at BPAS, the contraception and abortion charity.

CanFASD, Canada’s leading FASD research network, stated the article presents potentially harmful information about pregnancy and alcohol.

CanFASD agrees that although conversation around compassionate, non-judgmental ways to communicate this message to women and expectant mothers is indeed important—the current recommendations do not overstate risk, nor do they remove a woman’s right or ability to make a choice, rather, they provide clear, essential information in order that she may do so.

Providing women with accurate information and a supportive, safe environment to make the healthiest choice for herself and her developing baby are essential in reducing prevalence of FASD.

What can be said is that despite all the studies, there is no known safe amount of alcohol one can consume while pregnant. And that alcohol is a known teratogen.

A teratogen is an agent, which can cause a birth defect. Examples are prescribed medication, street drugs, alcohol, or a disease present in the mother which could increase the chance for the baby to be born with a birth defect. About 4 to 5 percent of birth defects are caused by exposure to a teratogen.

I have always said in my conversations with people about alcohol and pregnancy that how can anyone think alcohol does not affect the baby. Alcohol alters our state. It has to have some effect on a developing embryo. So why take the risk.

If you are trying to conceive or are pregnant, both moms and dads to be should just pass on the glass of alcohol. And if you discover you are pregnant after consuming alcohol, speak to your health care provider. Outcomes for all are better with earlier identification and intervention. No stigma. No shame.

2018 Update:

Check out FASD: It’s time to Stop the Debate. for another Study published after this original post and the reactions.

Another article:


talks about the need to abstain from alcohol by both sexes if planning a pregnancy.

We have known for many years that drinking alcohol during pregnancy can lead to developmental delays and birth defects in offspring. However, our data demonstrate that drinking large quantities of alcohol in a “binge” fashion before pregnancy can also impact future offspring and importantly, this is true for drinking behaviors of both parents, not just the mother.

Our previous data support the idea that alcohol is affecting the parental sperm and eggs to induce these modifications in the offspring, but this most recent work shows the extent of those effects on social behavior, pubertal maturation, and stress hormones as the offspring grow to adulthood.

This means that the risky behaviors of young people, such as the extremely popular practice of binge drinking, have potentially far-reaching consequences for generations to come.

More information will be shared on the effects of paternal alcohol consumption. For now, here is a link to the article and study: Prevention Conversation.

2019 Update:

An economics professor wrote a book a few years ago and suggested her research showed there was no evidence to say light drinking caused any harm. There was backlash then and in 2019 an updated version appeared, and she kept her position that it was okay to drink during pregnancy.

Here is a blog post about this from May 2019: A Tale of Two Books for Moms To Be

A fellow FASD advocate found the response below after the original publication of Expecting Better, which I felt was important to copy here so if you need back up to the debate, you can quote from this article by Susan Astley Ph.D. – a professor of Epidemiology and Pediatrics at the University of Washington and director of the Washington State FAS Diagnostic & Prevention Network of clinics (

The Conventional Pregnancy Wisdom is Right – Do NOT Drink while Pregnant

Once again, here comes a book “Expecting Better: Why the Conventional Pregnancy Wisdom is Wrong—And What You Really Need to Know” where the author Dr. Emily Oster, a professor of economics at the University of Chicago, reassures pregnant women that drinking just one alcoholic drink a day during pregnancy is safe. To the contrary, the conventional pregnancy wisdom is right— and here is what you really need to know.

First, a little history to set the stage… The year 2013 marks the 40th anniversary of the coining of the term fetal alcohol syndrome (FAS) in the medical literature. But 1973 was not the year we discovered the dangers of alcohol use during pregnancy. Clear reference to this danger dates back to biblical times “Behold, thou shall conceive, and bear a son; and now drink no wine or strong drink…Judges 13:7”.

Individuals with FAS have severe, lifelong brain damage caused by their mother’s use of alcohol during pregnancy. Although we have made tremendous progress over the past 40 years educating women and medical professionals about the dangers of alcohol use during pregnancy, the challenge continues.

The latest challenge is coming from women pushing back against public health notices like the Surgeon General’s Advisory “There is no known safe amount of alcohol to drink while pregnant”. Apparently we, the medical profession, have taken all the fun out of pregnancy. Surely this public health message is too conservative, too overly protective. After all-how much damage could a single drink a day possibly do?

Helping to fuel this pushback are headlines from two recent studies out of Denmark and Ireland claiming drinking is safe. Add to this the release of Dr. Oster’s book in August 2013 and you have the perfect storm.

In an interview with the Wall Street Journal, Dr. Oster reports “When I looked at the data from hundreds of studies, I found, basically, no credible evidence that low levels of drinking (a glass of wine or so a day) have any impact on your baby’s cognitive development”.  She goes on to report “The key to good decision making is evaluating the available information—the data—and combining it with your own estimates of pluses and minuses. As an economist, I do this every day.”

Well, as a Professor of Epidemiology and Pediatrics, director of an FAS diagnostic clinic that has diagnosed over 2,550 individuals with fetal alcohol spectrum disorders (FASD) over 20 years, and creator of one of the largest FASD databases, I too do this every day. As an economist, Dr. Oster concludes a drink a day during pregnancy is safe. As a pediatric epidemiologist, I conclude a drink a day is not safe. So which of us is correct?

I had an opportunity to speak with Dr. Oster the other day. We have a bit in common. We are both professors. We both crunch numbers for a living. And I do believe we both care deeply about the well- being of children. In preparation for our conversation, I had my FASD database open, ready to answer any question she may have.

She asked me “What proportion of children born with FAS were exposed to only 1 drink per day?” I think she expected me to say a drink per day cannot cause FAS. But my answer was “1 out of every 14 children we have diagnosed with full blown FAS over the past 20 years had a reported exposure of just 1 drink per day”. In fact, one of these children was reported to have been exposed to just 1 beer per day for the first 4 months. While it is true that the majority of children born with FAS were exposed to higher levels of alcohol, some (like this child) were exposed to just 1 drink a day.

So how can this be true? How could peer-reviewed published studies like the Danish and Irish studies fail to find an effect? How could Dr. Oster, a University professor, review the medical literature and come to the wrong conclusion?
Let me illustrate how this happens.

1. Danish researchers studied 870 preschool children whose mothers drank during pregnancy and compared them to 758 preschool children whose mothers did not drink during pregnancy.

They concluded that drinking up to 8 alcoholic drinks per week during pregnancy had no effect on children’s’ intelligence or attention levels. Headline: Moderate drinking during pregnancy branded ‘safe’.

But wait… if you look at the 2,550 alcohol-exposed children who received FAS diagnostic evaluations in the WA State FAS clinics over the past 20 years:

1 out of every 7 children diagnosed with full FAS (the most severe outcome of alcohol exposure) had a reported exposure of 1-8 drinks per week. (The Danish study did not conduct FAS diagnostic evaluations on the children);

Half of the children with FAS in our clinic had developmental scores in the normal range as preschoolers. But all had severe brain dysfunction confirmed by age 10. (The Danish study only assessed preschoolers);

Only 10% of our children with FAS had attention problems by age 5. 60% had attention problems by the age of 10. (The Danish study only assessed attention at age 5);

Only 30% of our children with FAS have an IQ below normal. But 100% had severe dysfunction in other areas like language, memory, and activity level (The Danish study did not assess these other areas).

2. Irish researchers studied over 5000 alcohol-exposed pregnancies and concluded that women who drink in early pregnancy, even those who binge drink, are not at increased risk for having a premature baby, a low birth weight baby, or a pregnancy complicated by preeclampsia.

Headline: Drinking early in pregnancy not associated with worse outcomes.

But hold on, if you look at the 2,550 children from our FAS clinic: The vast majority of children born with full blown FAS were NOT born premature (62.4%), were NOT low birth weight (75.9%), and were NOT the result of a pregnancy complicated by preeclampsia (99.4%). (The Irish study looked at outcomes that are very insensitive measures of the adverse effects of prenatal alcohol exposure).

3. One final example: Dr. Oster (an economics professor) reviews the medical literature on FASD and concludes it is safe to drink 1 drink a day during pregnancy.

But once again, if you look at the 2,550 children from our FASD clinic: 1 out of every 14 children diagnosed with full FAS were exposed to just 1 drink a day.

What these examples illustrate is: The studies are not incorrect, but each one taken individually is limited in scope.

Children with prenatal alcohol exposure (even children with full blown FAS) look deceptively good as preschoolers.

They will not show the full impact of their alcohol damage until they reach grade school.

To conclude that moderate drinking is OK based on the Danish study of 5 year olds would be a tragic mistake.

And there is long list of adverse outcomes that drinking during pregnancy is not strongly associated with (preeclampsia being one), but that does not make drinking during pregnancy safe.

These studies, if you read them carefully, do NOT conclude drinking during pregnancy is safe. It’s the press headlines and social media making these claims. These headlines have a major influence on women’s behavior and place real children at real risk.

Bottom line – some children are especially vulnerable to the damaging effects of alcohol. Which children are most vulnerable? We have no way of knowing because risk is not just based on how much alcohol the mother drank. We know from twin studies that genetics also plays a role. When genetically different twins are exposed to the same levels of alcohol, one twin can be born with FAS while the other twin is normally developed.

Now you see why the Surgeon General’s Advisory states there is no known safe amount to drink during pregnancy. The goal of that message is to protect ALL children, especially the most vulnerable like the child born with FAS whose mother drank only 1 beer a day. He turns 20 years old this year. Rather than live an independent, productive life, he will require support and assistance lifelong. Ask him if a drink per day is OK.

If you are pregnant or planning on getting pregnant, please do not drink. If you are unable to stop drinking, please contact us. We are here to help you and your child.

2020 Update:

After the 2019 edition of 99 Days was created, yet another article was published with evidence of the harm of alcohol.  

No Safe Amount of Alcohol During Pregnancy, Suggest Researchers

An international group of researchers has taken one of the first major steps in finding the biological changes in the brain that drive fetal alcohol spectrum disorders (FASDs). New work using chaos theory to analyze brain signals, discussed this month in the journal Chaos, from AIP Publishing, shows the long-term effects.

The group’s efforts mark one of the first times researchers have been able to quantify the effects of alcohol exposure on the developing brain.

“This work presents major evidence that children exposed to alcohol prenatally are at risk of suffering from impaired cognitive abilities and other secondary factors,” said Lin Gao, an author on the paper. “Our study … shows that there is no safe amount or safe stages during pregnancy for alcohol consumption.”

2022 Update:

New Study Shows Low Levels of Alcohol Has Negative Associations

A study released in April 2022 Evaluation of Brain Alterations and Behavior in Children With Low Levels of Prenatal Alcohol Exposure by Long & Lebel, came to the following conclusion:

In this cross-sectional study, we found structural brain alterations and worse behavior problems in children with low levels of PAE compared with a well-matched group of unexposed controls. Specifically, children with PAE had alterations in diffusion imaging metrics in left postcentral, parietal, temporal, and bilateral occipital white matter and in the gray matter of the putamen. These results suggest that even small amounts of prenatal exposure may lead to structural alterations of the brain, underscoring the importance of evidence-based policy recommendations and considering prenatal exposures in future studies of pediatric brain development.

You can learn more about the Study and results by clicking on the link above, or check out this episode of The FASD Success podcast with Dr. Lebel: #104 Dr. Catherine Lebel: New Study on low levels of prenatal alcohol exposure

Stay tuned for more information about the effects of alcohol throughout a pregnancy – including more research on the role of paternal alcohol consumption.

Come back tomorrow for another tip in the 99 day countdown to FASDay. 94 to go!

2022 graphic

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